Hi there! I understand that your Bejeweled Blitz game loads but when you try to play, the mouse freezes. Let's get to the bottom of this so you can enjoy your game smoothly.

Just to clarify, are you playing directly in your browser on Windows 10 using a WebKit-based browser, right? Also, does the mouse freeze only happen when the game starts, or does it freeze intermittently during gameplay? Any recent changes like browser updates or system changes?

Meanwhile, here's a step-by-step approach we can try to fix the mouse freezing issue during gameplay:

1. Clear Browser Cache and Cookies
Sometimes residual data causes conflicts. Clear your browser’s cache and cookies, then restart the browser and try launching the game again.

2. Update Your Browser
Make sure your WebKit-based browser is up to date. Older versions can cause compatibility issues with games like Bejeweled Blitz.

3. Close Other Tabs and Background Applications
Running many tabs or heavy applications can sometimes interfere with mouse input. Close unnecessary tabs and applications and test again.

4. Check Browser Hardware Acceleration
Sometimes hardware acceleration can cause input or rendering issues. Try toggling it off or on in your browser settings and see if that improves things.

5. Try Running the Game in a Different Browser
If possible, test the game using another browser like Chrome or Firefox to see if the problem is browser-specific.

6. Update Your Mouse Drivers
Outdated or corrupt mouse drivers on Windows 10 could cause freezing during input-heavy applications like games. Go to Device Manager, find your mouse, and update the driver.

7. Disable Browser Extensions
Sometimes extensions interfere with games. Disable any non-essential browser extensions and test.

If after trying the above the mouse still freezes, there's a known helpful tip from the gaming community:
Some users have reported that running the game in full-screen mode instead of borderless windowed mode resolves freezing or mouse issues. Check if your browser or game settings allow toggling between these display modes and give it a shot5.

Let me know which steps you've tried so far or if you'd like me to guide you through any of these in detail! We'll get this sorted.